The U. The chewable tablet may contain phenylalanine and could be harmful if you have phenylketonuria PKU. Get emergency medical help if you have signs of an allergic reaction: hives, blisters, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your doctor right away if you have signs of blood vessel inflammation : flu-like symptoms, severe sinus pain, a skin rash, numbness or a "pins and needles" feeling in your arms or legs.
Some people using montelukast have had new or worsening mental problems. Stop taking this medicine and call your doctor right away if you have unusual changes in mood or behavior, such as:. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs nonsteroidal anti-inflammatory drugs such as ibuprofen Advil, Motrin , naproxen Aleve , celecoxib, diclofenac, indomethacin, meloxicam, and others.
Use Singulair Montelukast exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Use the medicine exactly as directed. Montelukast is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working. For exercise-induced bronchoconstriction, take a single dose at least 2 hours before exercise, and do not take another dose for at least 24 hours.
Place the oral granules directly in your mouth and swallow, or mix them with applesauce, mashed carrots, rice, or ice cream. The granules may also be mixed with baby formula or breast milk.
Do not use any other type of liquid. Use the mixture within 15 minutes. Do not save for later use. In the Rumor vs. Truth section of the Pharmacists Letter evaluating when montelukast should be dosed, they concluded asthma symptoms tend to be worse during the night and early morning hours and that montelukast has a short half-life of about hours with blood levels peaking hours after a dose.
This would argue that evening dosing would have the most significant benefit on asthma symptoms both during sleep and the next day 4. No clinical data could be found supporting this comment. Since the publication from the Pharmacist Letter, there has not been any additional studies or trials conducted to compare morning versus evening dosing of montelukast. With the question still slightly up in the air, I would still recommend the use of montelukast in the evening, despite there being no clinical evidence in comparing morning doses versus evening doses in adults with asthma.
I say this because from clinical trials comparing placebo versus montelukast, montelukast was always given in the evening showing statistical significant results in reducing asthma symptoms in children and adults. Accessed July 27, Speak to your doctor if you become pregnant while you are taking montelukast. If your doctor or health visitor says your baby is healthy, you can take montelukast while you're breastfeeding.
Montelukast passes into breast milk in small amounts. The benefits of the medicine are greater than the small risk of side effects in your baby.
If you notice that your baby is not feeding as well as usual, seems unusually sleep, or if you have any other concerns about your baby, talk to a health visitor or doctor immediately. It's usually safe to take everyday painkillers with montelukast. However, do not take non-steroidal anti-inflammatory drugs NSAIDs such as aspirin or ibuprofen if they have ever made your asthma symptoms worse.
There's very little information about taking herbal medicines and supplements with montelukast. Ask a pharmacist for advice. Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
Montelukast is from a group of medicines called leukotriene receptor antagonists LTRAs. LTRAs work by stopping the chemicals in your body that narrow your airways. These chemicals are called leukotrienes. Montelukast helps stop your airways from narrowing caused by inflammation. This makes breathing easier and prevents asthma attacks. Leukotrienes are also released in your body when you have an allergic reaction to something like dust or pollen and when you exercise.
Montelukast helps to reduce the level of leukotrienes and stops you getting symptoms. Montelukast starts to work immediately to reduce leukotriene levels in your body which make your symptoms worse.
However, it may take around a week before it reaches its full effect. If you're taking montelukast to prevent exercise-induced asthma, take it 2 hours before you exercise.
This will mean that the levels of medicine in your body is highest when you start exercising. Take montelukast for as long as your doctor recommends it. It will only keep working while you are taking it. There's no evidence to suggest that taking montelukast will cause any problems if taken for a long time. Most people with asthma will be given an inhaler such as beclomethasone or fluticasone. Montelukast may be given as an extra medicine if your doctor thinks you need it.
Other medicines which may help prevent asthma attacks are inhalers like salmeterol or sodium cromoglycate, or medicines like theophylline. Montelukast does not affect any type of contraception including the combined pill and emergency contraception.
Read more about what to do if you're taking the pill and you're being sick or have diarrhoea. There is no firm evidence to suggest that taking montelukast will reduce fertility in either men or women. Montelukast does not usually cause any problems with driving or riding a bike. Do not drive a car or ride a bike if montelukast makes you see things which are not there hallucinate , if you get shaking or tremors in any part of your body or you're unable to concentrate or make decisions.
It's your responsibility to decide if it's safe to drive. If you're in any doubt, do not drive. Page last reviewed: 25 February Next review due: 25 February Montelukast - Brand name: Singulair On this page About montelukast Key facts Who can and cannot take montelukast How and when to take it Side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.
About montelukast Montelukast is used to prevent the symptoms of asthma. Important Do not use montelukast to treat an asthma attack. Help us improve our website Can you answer a quick question about your visit today?
Most people take montelukast once a day in the evening. If you take it for asthma, it's important to take it even when you have no symptoms. Montelukast is used alongside your inhalers or other asthma medicine.
Some common side effects include headaches and feeling or being sick.
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